How Soon After Ivf Birth Can You Try Again

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Adept odds for second IVF baby success

Women with 1 IVF baby have a expert chance of giving them a little brother or sister, finds the first study to investigate the odds of having a 2nd child via assisted reproductive technology treatment.

The analysis of more than than 35,000 women found the chances of having a 2d IVF infant was 43 per cent later one bike with frozen embryos and 31 per cent with fresh embryos.

Kristy and Andrew Pownall with their children, Noah, two and newborn Grace, who were both conceived through IVF. Credit:Janie Barrett

Later on 3 cycles, the chances rose to between 60 and 81 per cent for frozen embryos and 47 to 56 per cent for fresh cycles, the authors led by researchers at the University of NSW's National Perinatal Epidemiology and Statistics Unit, found.

The report, published on Friday in the periodical Human Reproduction, is the starting time to report the chances of having a second IVF baby amid women using their own eggs, confirming the older the female parent the lower the odds, and the potency of younger, frozen embryos.

Senior study author Professor Georgina Chambers said the findings would empower IVF patients past providing them with the hard data they accept been asking for to help them decide whether they volition effort for a 2d baby.

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"We know that many women and couples want more than than one baby to complete their family, and they want to be fully informed," Professor Chalmers said.

"This data should reassure them that their chances of having a second baby through IVF is very adept."

The researchers studied 35,290 women who underwent IVF treatment using their own eggs at 90 clinics throughout Australia and New Zealand and gave birth to live babies between 2009 and 2013.

They followed the women for some other 2 years and included subsequent births upwards to Oct 2016.

Just over 43 per cent (xv,325 women) tried for another IVF-conceived child. Their median historic period was 36, and 73 per cent had frozen embryos from the egg retrieval that created their offset baby.

For these women, the chances of having a second IVF babe ranged from 61 per cent (a conservative guess) to 88 per cent (the optimal estimate) after 6 cycles. For fresh embryos, the range was 51-70 per cent.

Frozen embryos collected when the women were younger were more probable to be successful compared to fresh embryos. Couples whose infertility was due to a cistron affecting the male partner also had a greater gamble of success.

The older the mother, the lower the chances.

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For women anile 30-34, the chances of having a 2d IVF babe after one cycle was 48 per cent with frozen embryos and 43 per cent with a fresh cycle. Afterward three cycles, 69-ninety per cent would take home their second baby from a frozen embryo, and 62-74 per cent from fresh ones.

Women aged xl-44 had a 29 per cent chance of having a second baby with frozen embryos from their get-go bike and 12 per cent with fresh embryos, Professor Chalmers said.

The conservative figure assumes that women who didn't return for more IVF treatment would accept no take chances of achieving a second babe if they had continued treatment, and the optimal approximate assumed these women would have the same chance of a alive birth in a particular cycle as women who had continued treatment.

The range between the two offers women a realistic idea of the truthful success rates, the authors said.

"For older women, the findings are still reassuring that even in the xl-44 age group the chances of having a second infant through IVF using your ain eggs are practiced, not very good, but yet good," Professor Chalmers said. "But it'due south best non to expect too long," she said.

Kristy Pownall gave nativity to her daughter Grace seven weeks ago. Just like her 2-year-old brother, Noah, Grace conceived via a frozen embryo.

The siblings are also "rainbow babies" - children born after the loss of an unborn child. Noah was conceived after Kristy and her husband Andrew lost her first baby, Amelie, at 20 weeks, and Grace was conceived afterwards Ms Pownall miscarried.

"At my age [42 years old] I experience very lucky to take ii babies. Babies I have wanted for many years," Ms Pownall said.

When she went back to try for a second IVF baby, she didn't wheel through the feelings of hopelessness and anxiety she had felt in the years of IVF treatment before having Noah.

Kristy and Andrew Pownall with their children, Noah, ii and Grace, who were both conceived through IVF. Credit:Janie Barrett

"Back then I had all this worry when I would call up 'if I can't take a babe, if I can't exist a female parent, what would my life await like?," Ms Pownall said.

"At present we just really bask every moment we accept with Noah and Grace."

Sydney fertility specialist and study co-author Dr Devora Lieberman ofttimes talks with her patients about the possibilities of having multiple children before they have conceived.

"We have moved away from talking nearly one baby to talking about what your platonic family unit size looks like," Dr Lieberman said.

She said the findings did not take into business relationship all individual factors that can bear upon a woman's chances, such as the duration of infertility, body mass index and smoking condition.

"Ultimately the decision to try for another baby is for the patient, her md, and considers all the medical and non-medical factors," Dr Lieberman said.

Dr Karin Hammarberg, an IVF academic and senior research young man at Monash University's School of Public Health and Preventive Medicine, said the report gave women and couples the hard information they wanted.

"The manner IVF is promoted yous would think everyone has a baby the first get … it's much more useful for patients to know that it is quite possible they might have to have three cycles, what their chances may be and give them the courage to come back," Dr Hammarberg said.

"If you are lucky plenty to have a baby and still have frozen embryos in the tank your chances of having that second kid are much greater."

She said it would as well help patients recall of their IVF handling on a continuum - an ongoing procedure, rather than in single cycles that failed or succeeded, by understanding many women needed several cycles earlier they got to accept domicile a baby.

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Source: https://www.smh.com.au/national/good-odds-for-second-ivf-baby-success-20200508-p54r0g.html

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